91吃瓜

Personal profile
Feng Siyuan, Associate Professor, Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University. In 2018, he received his PhD in Immunology from Sun Yat-sen University. From 2018 to 2023, he worked as a postdoctoral fellow/special researcher in Zhongshan Medical College.

Academic achievement
Representative treatise

1. Li J*, Feng S*, Chen Y, Yu M, Wei W,  Tian GB#. Antimicrobial susceptibility testing in clinical Mycobacterium tuberculosis isolates. Lancet Microbe. 2023  Feb; 4(2):e68. doi: 10.1016/S2666-5247(22)00299-3. (Co-first author, District 1, Chinese Academy of Sciences, impact factor 86.208)
2. Feng S*, Liang L*, Shen C*, Lin D, Li J, Lyu L, Liang W, Zhong LL, Cook GM, Doi Y, Chen C,  Tian GB. A CRISPR-guided mutagenic DNA polymerase strategy for the detection of antibiotic-resistant mutations in M.  tuberculosis. Molecular Therapy-Nucleic Acids. 2022 Jul 12; You 4-367 doi: 10.1016 / j.o MTN. 2022.07.004. (first author together, the area of Chinese Academy of Sciences, impact factor of 10.183)
3. Feng S*, Liang W*, Li J, Chen Y, Zhou D, Liang L, Lin D, Li Y, Zhao H, Du H, Dai M, Qin LN, Bai F, Doi Y#, Zhong LL#,  Tian GB#. MCR-1-dependent lipid remodelling compromises the viability of Gram-negative bacteria. Emerging Microbes &  Infections. 2022 Dec; 11 (1) : 1236-1249. The doi: 10.1080/22221751.2022.2065934. (the first author together, the two areas of Chinese Academy of Sciences, impact factor of 19.568)
4. Liang L*, Lin D*, Chen Y*, Li J*, Liang W, Zhao H, Luo W#, Tian GB#,  Feng S#. Single-Fluorescence ATP Sensor Based on Fluorescence Resonance Energy Transfer Reveals Role of  Antibiotic-Induced ATP Perturbation in Mycobacterial Killing. mSystems. 2022 May 26; e0020922. Doi: 10.1128/msystems.00209-22. (Co-corresponding author, Second Region, Chinese Academy of Sciences, Impact factor 7.324)
5. Feng S*, Wu Z*, Liang W*, Zhang X, Cai X, Li J, Liang L, Lin D, Stoesser N, Doi Y, Zhong LL, Liu Y, Xia Y, Dai M,  Zhang L, Chen X#, Yang JR#,  Tian GB#. Prediction of Antibiotic Resistance Evolution by Growth Measurement of All Proximal Mutants of Beta-Lactamase.  Molecular Biology and Evolution. 2022 May 3; 39(5):msac086. doi: 10.1093/molbev/msac086. (Co-first Author, Region 1, Chinese Academy of Sciences, impact factor 8.800)
6. Feng S*, Hong Z, Zhang G, Li J, Tian GB, Zhou H,  Huang X#. Mycobacterium PPE31 Contributes to Host Cell Death. Frontiers in Cellular and Infection Microbiology. 2021 Apr 13; But 29836. Doi: 10.3389 / fcimb. 2021.629836. (the first author together, the two areas of Chinese Academy of Sciences, impact factor of 6.073)
7. Yang F*, Xu L*, Liang L*, Liang W*, Li J, Lin D, Dai M, Zhou D, Li Y, Chen Y, Zhao H, Tian GB,  Feng S#. The Involvement of Mycobacterium Type III-A CRISPR-Cas System in Oxidative Stress. Frontiers in Microbiology.  2021 Dec 9; "74492. Doi: 10.3389 / fmicb. 2021.774492 eCollection 2021. (independent corresponding author, the Chinese Academy of Sciences 2 area, impact factor 6.064)
8. Feng S*, Liu Y*, Liang W, Ahmed MAEE, Zhao Z, Shen C, Roberts AP, Liang L, Liao L, Zhong Z, Guo Z, Yang Y, Wen X,  Chen H#, Tian GB#. Involvement of Transcription Elongation Factor GreA in Mycobacterium Viability,  Antibiotic Susceptibility, and Intracellular Fitness. Frontiers in Microbiology. 2020 Mar 23; So 3. Doi: 10.3389 / fmicb. 2020.00413 eCollection 2020. (the first author together, the two areas of Chinese Academy of Sciences, impact factor of 6.064)
9. Shen C*, Feng S*, Chen H*, Dai M*, Paterson DL, Zheng X, Wu X, Zhong LL, Liu Y, Xia Y, Ma R, Huang X,  Tian GB#. Transmission of mcr-1-Producing Multidrug-resistant Enterobacteriaceae in Public Transportation in Guangzhou,  China. Clinical Infectious Diseases. 2018 Nov 13; 67(suppl_2):S217-S224. doi: 10.1093/cid/ciy661. (Co-first Author, District 1, Chinese Academy of Sciences, Impact factor 20.999)

Scientific research project
1. National Natural Science Foundation of China (32070959), 2021-2024, Project leader, 580,000 yuan
2. National Natural Science Foundation of China Youth Project (81601104), 2017-2019, Project leader, 170,000 yuan
3. Guangdong Natural Science Foundation Free Application Project (2017A030313862), 2017-2020, Project leader, 100,000 yuan
4. China Postdoctoral Science Foundation (2016M602591), 2016-2017, Project leader, 50,000 yuan
5. Major Project of Industry-University-Research Collaborative Innovation of Guangzhou Science and Technology Planning Project (201704020066), 2017-2020, Project leader, 1 million yuan
6. College Basic Research Fund for Young Teachers Training Project (19ykpy160), 2019-2021, Project leader, 200,000 yuan
7. Stem Cell Research and Organ Repair Project of National Key Research and Development Program for Young Scientists (2022YFA1105900), 2022-2027, project backbone, 5 million yuan
8. National Natural Science Foundation of China - Guangdong Joint Fund Integration Project (U1801681), 2019-2022, main member of the project team, 11.8 million yuan
9. Guangdong Province Key Areas Research and Development Program "Brain Science and brain-like research" major science and technology project (2018B030337001), 2019-2022, main research and development personnel, 44.8 million

Award honor
He has presided over five scientific research projects, including National Nature Surface project, Youth Project, and Guangdong Province Natural Surface Project. At the same time, he has participated in one national nature key international cooperation research project and one national nature key project as the core backbone. The results were published as first or corresponding author in Lancet Microbe, Molecular Biology and Evolution, Clinical Infectious Diseases, Emerging Microbes & Infection and other international top journals in the field have published 9 SCI papers. Applied for 2 invention patents.